
McKesson leads the charge in revolutionizing precision oncology in community practices
Precision medicine has become the cornerstone of cancer care over the last decade. In 2024, the U.S. Food and Drug Administration approved 48 precision medicine treatments, according to Precision Medicine Online, up from 28 in 2023,1 with many more in the pipeline.2 While these promising treatments are transforming care and extending lives, the complexity of the precision oncology landscape can present challenges for community oncology practices, where approximately 80% of people with cancer in the U.S. receive their care.3
Given the rapid changes, community practices must find innovative, effective ways to keep pace with these dynamic advancements to ensure oncology patients have access to the best care. Clinical and operational adjustments must be made to accommodate these new therapies, but change is not always easy. However, by pairing technology with education and improved processes, community oncology practices can efficiently implement practical solutions to drive biomarker testing and targeted therapy utilization, ushering in a digital transformation that can unlock the potential of precision medicine at the community level.
Challenges to accessing precision medicine
Community practices, especially those in rural and underserved areas, treat patients with a wide variety of cancers requiring expansive expertise and current knowledge across many domains.4 Many patients eligible for precision treatments never receive them or disengage during treatment5 due to delayed or missed biomarker testing, treatment initiation before biomarker results are received, incomplete biomarker assessments, and inaction on test results.6 A range of issues, including insufficient technical support, lack of biomarker testing and diagnostic tools, slow lab times, inefficient workflows, and low clinical trial enrollment, all inhibit the effective delivery of precision medicine.
Harnessing technology to integrate precision medicine into practices—pairing technology with customized workflows and education—may offer a solution. For example, electronic health records (EHR) embedded with clinical and administrative tools can support precision oncology, offering providers biomarker ordering guides and test results that populate in the workflow. EHRs can link to National Comprehensive Cancer Network Guidelines, further streamlining workflows,7 and processes can be adjusted so biomarker testing is part of standard of care. Technology can also play a crucial role in education and training, enabling personalized learning experiences to help staff understand their role in delivering these cutting-edge therapies.
Practices with research capabilities can expand access to targeted therapies through clinical trials, which should be the first option for patients, not the last. Artificial Intelligence (AI) can efficiently identify trials that may be appropriate for patients, further expanding access to care.

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McKesson is empowering community oncology to deliver precision care, improving patient outcomes
For decades, McKesson has offered market-leading solutions that enable community oncology to deliver superior care while remaining financially strong and independent. Advanced technologies, analytics that deliver actionable insights, clinical research support, and expertise and guidance in clinical and operational areas have helped practices thrive, overcoming the many hurdles created by the ever-changing healthcare landscape.
Today the tradition continues, with McKesson at the forefront of providing community oncology with innovative technologies and resources specifically designed to drive and support precision medicine. Its revolutionary Precision Care Companion (PCC) is a transformative initiative designed to help community practices transition to more biomarker-driven cancer care. A comprehensive solution, PCC enables precision medicine to be seamlessly integrated and implemented by helping practices overcome the clinical and administrative challenges they face when delivering complex targeted therapies.
“Precision Care Companion is a testament to McKesson’s strong, ongoing commitment to community oncology, enabling providers to efficiently bring targeted, personalized cancer care to their local community,” said Jason Hammonds, chief operating officer of Oncology & Specialty for McKesson. “This all-inclusive solution accelerates development of new treatments while providing practices with cutting-edge technology and real-world evidence that drives improved outcomes and advances community cancer care.”
PCC is a consortium of industry experts providing a multi-faceted solution that includes resources tailored to individual practice needs, such as targeted education, advanced technologies, best practices, and detailed analytics on biomarker testing rates for different cancers. The program includes technology improvements and additional lab interfaces with Ontada’s market-leading iKnowMedSM EHR, enabling enhanced clinical decision support for precision medicine.
The model unites diverse perspectives from physicians, clinicians, industry partners, and business leaders, fostering collaboration to accelerate usage of precision technology and therapies. Educational and consultative services specifically tailored to individual needs are available, including webinars, a precision medicine boot camp, a molecular helpline for urgent questions about specific biomarker test results, and molecular tumor boards.
PCC is currently being deployed across The US Oncology Network, an organization supporting more than 2,700 independent, community-based providers. The PCC team assists participating practices during each step of the care journey—from test ordering and results review to guideline-informed targeted therapy decisions. This consultation is invaluable, as providers may struggle to keep up with new research. Researchers are rapidly identifying molecular abnormalities that fuel subsets of common tumors, and drugs are swiftly being developed to target them. Input from the PCC team may increase provider confidence and can help ensure patients receive optimal treatments, especially for rare cancers. The team also provides guidance concerning the frequency of biopsies and what action to take if clonal evolution occurs.
McKesson is also advancing precision oncology through other initiatives. In 2022, it formed a joint venture with HCA Healthcare’s Sarah Cannon Research Institute (SCRI). This joint venture established a fully integrated oncology research organization aimed at expanding clinical research, accelerating drug development, and increasing availability and access to clinical trials for community oncology providers and patients, including those in underserved communities. McKesson also acquired Genospace, a leading-edge software company that integrates clinical, genomic, and real-world data, enabling personalized treatment strategies and improved outcomes.
“Genospace is a leading innovator in precision medicine and clinical trial matching,” said Andrew McKenzie, PhD, vice president, Personalized Medicine, SCRI; Scientific Director, Genospace. “Our advanced technologies and analytics capabilities push the boundaries of what is possible in precision medicine, enhancing the ability of community providers to more efficiently identify appropriate therapies and trials for their patients.”
With Precision Care Companion, SCRI and Genospace, McKesson continues its long tradition of pioneering innovative solutions that empower community oncology practices to deliver cutting-edge, personalized cancer care close to home.
Learn more about McKesson here.
References:
- Bryne A. McKesson Looks to Improve Precision Oncology Access in Community Practice With New Consortium. Precision Medicine Online. Apr 25, 2025. Accessed May 4, 2025. https://www.precisionmedicineonline.com/precision-oncology/mckesson-looks-improve-precision-oncology-access-community-practice-new
- Lottering B. Key Trends in the Pharmaceutical Pipeline for 2024 — Part I: Transformative R&D Growth Driven by Breakthroughs in Oncology, Neurological, and Metabolic Therapies. GeneOnline. October 18, 2024. Accessed April 27, 2025. https://www.geneonline.com/key-trends-in-the-pharmaceutical-pipeline-for-2024-part-i-transformative-rd-growth-driven-by-breakthroughs-in-oncology-neurological-and-metabolic-therapies/
- Association of Cancer Care Centers. Quality Improvement Collaboration: Integration of Precision Medicine in Community Oncology. ACCC. 2025. Accessed April 28, 2025. https://www.accc-cancer.org/home/learn/precision-medicine/quality-improvement-collaboration-integration-of-precision-medicine-in-community-oncology
- ibid.
- ibid.
- ibid.
- Neubauer M, Moodley S. Precision Medicine Implemented in the Community Oncology Setting. Targeted Therapies in Oncology. March I, 2024. Volume 13, Issue 3. Accessed May 3, 2025. https://www.targetedonc.com/view/precision-medicine-implemented-in-the-community-oncology-setting